Dey Lab

We develop novel single-cell sequencing technologies to study how variability in
the epigenome regulates gene expression heterogeneity and cell fate decisions

Our lab is located on the beautiful UCSB campus!

Featured Publications

Combinatorial quantification of 5mC and 5hmC at individual CpG dyads and the transcriptome in single cells reveals modulators of DNA methylation maintenance fidelity | Nature Structural & Molecular Biology (Accepted) | 2023
Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development | Nature Communications | 2021
Simultaneous quantification of protein–DNA contacts and transcriptomes in single cells | Nature Biotechnology | 2019
Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction | Nature Biotechnology | 2016
Orthogonal control of expression mean and variance by epigenetic features at different genomic loci | Molecular Systems Biology | 2015
Integrated genome and transcriptome sequencing of the same cell | Nature Biotechnology | 2015

Contact

Email: [email protected]

Office:
3008 BioEngineering Bldg.
University of California, Santa Barbara
Santa Barbara, CA 93106-5080

Lab:
2206 BioEngineering Bldg.
University of California, Santa Barbara
Santa Barbara, CA 93106-5080

Join Us!

We are always looking for enthusiastic and motivated graduate students and postdocs to join our team. If you have a background in science or engineering and are excited to work on quantitative and fundamental problems in biology, please contact Sid at [email protected].

Postdocs: We have two openings for postdoc positions. Click here to learn more.

Incoming graduate students: If you are interested in the problems we work on, send Sid an email to set up a time to meet.